AUSTIN, Texas One of the grand challenges with using CRISPR-based gene editing on humans is that the molecular machinery sometimes makes changes to the
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Scientists Discover How Remdesivir Works to Inhibit Coronavirus
More effective antiviral treatments could be on the way after research from The University of Texas at Austin sheds new light on the COVID-19 antiviral drug remdesivir, the only treatment of its kind currently approved in the U.S. for the coronavirus.
Remdesivir targets a part of the coronavirus that allows it to make copies of itself and spread through the body. For the first time, scientists identified a critical mechanism that the drug uses and unearthed information that drug companies can use to develop new and improved antivirals to take advantage of the same trick.
Texas researchers studying the inner workings of remdesivir say their findings could be used to develop similar but more powerful drugs to help fight the coronavirus.
A bottle containing the drug remdesivir is held by a health worker in Debrecen, Hungary, last October. (Zsolt Czegledi/MTI via AP, File)
(CN) New science on how exactly the widely used antiviral drug remdesivir fights Covid-19 could lead to more powerful and easier-to-administer drugs of the same type, researchers said in a study published Thursday.
Remdesivir is still the only antiviral drug approved in the U.S. to treat Covid-19, though there are multiple other drugs of a different variety called monoclonal antibodies being used to treat patients with mild cases.