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Key Gene Found Responsible for Chronic Inflammation, Accelerated Aging and Cancer

Key Gene Found Responsible for Chronic Inflammation, Accelerated Aging and Cancer
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Robertj schneiderBreast cancer programSchool of medicineNational institutes of healthLangone medical centerAlbert sabin professorMolecular pathogenesisNational institutesMolecular cellLatest streaming newsChronic inflammationupdated

Exploring the role of protein barcodes and Next-Generation Protein Sequencing™ for protein conformation high-throughput mapping

Exploring the role of protein barcodes and Next-Generation Protein Sequencing™ for protein conformation high-throughput mapping
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San diegoUnited statesNew yorkStony brookEugene serebryanyJonathan rothbergAimee molineuxStony brook universitySponsored contentCorona borealisNext generation protein sequencingStony brook basedMolecular cellProtein misfoldingNature educationHematol oncol

Repurposed Protease Regulates Key Signaling Protein

Repurposed Protease Regulates Key Signaling Protein
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Fangfang luYingdi wangChia hsueh leeHongtu zhaoMatthew freemanYaxin daiJude department of structural biologyWellcome trust investigatorUniversity of oxfordNational institutes of healthJude children research hospitalMolecular cellJude childrenResearch hospitalJude departmentNational institutes

Repurposed protease controls important signaling molecule-activating protein

Efficient communication between cells is vital for many biological processes, such as recruiting immune cells to combat disease. The rapid release of at least 80 signaling molecules, including tumor necrosis factor and epidermal growth factor, is controlled by a membrane-bound protease called ADAM17.

Hongtu zhaoYingdi wangYaxin daiMatthew freemanChia hsueh leeFangfang luUniversity of oxfordJude department of structural biologyJude children research hospitalJude departmentStructural biologyJude childrenResearch hospitalMolecular cell

The beauty of biology

MIT biology student Hanjun Lee had planned to pursue chemistry at MIT. A course in genetics changed that, noting, “There’s a beauty in studying and finding the patterns in nature.”

Whitehead instituteUnited statesSouth koreaUnited kingdomSoult ukpyolsiMichael lawrenceStates leeHanjun leePeter reddienAviv regevCancer centerInternational chemistry olympiadGordon research conference on cell growthAmerican association for cancer research undergraduate scholarSeoul national universityResearch journal