Coincided this year but we kickoff the holiday season. What does that mean . It means that santa claus arrives at macys and officially opening the shopping season, even though this years on thanksgiving, some stores were open, its black friday, its now sign ber monday. Its a lot of things just coming altogether and you wonder when does it start and when does it end . It youd to be when the rocettes would dance and santa would come, and then you knew it would all over at the orange bowl. Because that was january 1st. And you had the the parade and then you had the rose bowl and then you had the orange bowl and then you went back to work and you thought, okay, thats the ho the day season. Well now, its a little bit more difficult than that, because after after the bowl games, which they now extend into the then you have the nfl and then you have the nfl and that goes into the first week of february. Superbowl and all of that. And all of that. So now the whole thing is extended to what i
TCR transgenic clone selection guided by immune receptor analysis and single cell RNA expression of polyclonal responders elifesciences.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from elifesciences.org Daily Mail and Mail on Sunday newspapers.
Known for her creative artistry, Alisa Deal captured the Booth Western Art Museum’s Purchase Award for “Tree Stars.” The 12-year-old’s artwork, which is featured in the 20th annual “Kids Cowboy
When snow and ice coats trees, it can be one of Mother Nature's most beautiful sights – until the branches get weighed down and break. Or worse, a tree falls.
Rabies is a lethal zoonotic disease that is mainly caused by the rabies virus (RABV). Although effective vaccines have long existed, current vaccines take both time and cost to produce. Messenger RNA (mRNA) technology is an emergent vaccine platform that supports rapid vaccine development on a large scale. Here, an optimized mRNA vaccine construct (LVRNA001) expressing rabies virus glycoprotein (RABV-G) was developed in vitro and then evaluated in vivo for its immunogenicity and protective capacity in mice and dogs. LVRNA001 induced neutralizing antibody production and a strong Th1 cellular immune response in mice. In both mice and dogs, LVRNA001 provided protection against challenge with 50-fold lethal dose 50 (LD50) of RABV. With regards to protective efficiency, an extended dosing interval (14 days) induced greater antibody production than 3- or 7-day intervals in mice. Finally, post-exposure immunization against RABV was performed to evaluate the survival rates of dogs rec