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Single-cell profiling of human bone marrow progenitors reveals mechanisms of failing erythropoiesis in Diamond-Blackfan anemia

Single-cell profiling of human bone marrow progenitors reveals mechanisms of failing erythropoiesis in Diamond-Blackfan anemia
science.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from science.org Daily Mail and Mail on Sunday newspapers.

Eteläuomen läiPerifereia dytikis elladasUnited kingdomCity ofShandon cytospinMiltenyi biotecBlood cancer united kingdom clinical research fellowshipNational research ethics committeeNational institute of diabetesMiltenyi biotec ltdAcademy of medical sciences starter grantImperial college healthcareNational human genome research institute intramuralUnited kingdom research awardBritish society of haematology early stageImperial college london

A high-affinity human TCR-like antibody detects celiac disease gluten peptide–MHC complexes and inhibits T cell activation

A high-affinity human TCR-like antibody detects celiac disease gluten peptide–MHC complexes and inhibits T cell activation
sciencemag.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from sciencemag.org Daily Mail and Mail on Sunday newspapers.

South australiaUnited kingdomSjl ptprca pepcb boycrlAmyra gmbMiltenyi biotecDissociator miltenyi biotecStiftelsen kristian gerhard jebsenMmlv vectorbuilder gmbIntrexon actobioticsOslo university hospital or akershusNational infrastructure for high performance computingNorwegian food safety authority mattilsynetBritish society for gastroenterologyDepartment of comparative medicineResearch dietsDepartment of immunology at oslo university hospital

Lymphatic-specific intracellular modulation of receptor tyrosine kinase signaling improves lymphatic growth and function

Lymphatic-specific intracellular modulation of receptor tyrosine kinase signaling improves lymphatic growth and function
sciencemag.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from sciencemag.org Daily Mail and Mail on Sunday newspapers.

United statesSan diegoBaden wübergLeica microsystemsLecs promocellMillipore burlingameSakura finetekAbcam cambridgeQiagen hildenBiosciences franklin lakesLaboratory animalsHenry schein animal healthNational institutes of healthLight sources incCell signaling technology danversCommittee at memorial sloan kettering cancer center

Teplizumab improves and stabilizes beta cell function in antibody-positive high-risk individuals

Science for just $15 USD. Prolonged prevention of autoimmune diabetes Teplizumab was previously shown in a clinical trial to delay onset of type 1 diabetes (T1D) in high-risk relatives of individuals with T1D. Now, Sims et al. extend the follow-up analysis of this trial by 12 months, finding that efficacy of the initial 2-week treatment course persisted, with an extended time to T1D diagnosis in the teplizumab-treated group. Clinical benefits associated with reversed C-peptide decline improved beta cell function and partial exhaustion in CD8 + T cells in the treated patients. HbA1c did not differ between placebo and treatment groups. This follow-up study further supports the use of anti-CD3 treatment for the prevention of T1D.

United statesIowa cityMercy hospitalUniversity of floridaUniversity of miamiSan franciscoWilliame russellLindaa dimeglioDesmond schatzEva tsalikianStephene gitelmanAnette gabriele zieglerDianek wherrettProvention bioWayne moorePetera gottlieb

Dimitrios Grammozis wird neuer Trainer auf Schalke: Chef mit Probezeit

Dimitrios Grammozis wird neuer Trainer auf Schalke: Chef mit Probezeit
sueddeutsche.de - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from sueddeutsche.de Daily Mail and Mail on Sunday newspapers.

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