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The popular vacation gang is back with its awaited sequel Vacation Friends 2. The film starring John Cena, Lil Rel Howery, Meredith Hagner and Yvonne Orji will release on August 25. 20th Century Studios released a first look of the film as well. Check it out below. Vacation Friends 2 First Look Out! John Cena, Lil Rel Howery, Yvonne Orji, & Meredith Hagner Are Back for a Wild and Fun Ride.