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Researchers identify the mutations that drive resistance to PI3K inhibitors in breast cancer, find they can be overcome

Researchers identify the mutations that drive resistance to PI3K inhibitors in breast cancer, find they can be overcome
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United statesDejan juricBryan corcoranAndreas varkarisTermeer centerCancer centerGastrointestinal cancer centerTherapies investigational cancer therapeutics programCancer discoveryMass general cancer centerMass general brighamFerran fece de la cruzMass general cancerTargeted therapyTargeted therapiesInvestigational cancer therapeutics program

Genetic mutation diminishes drug response in some cancer patients

Researchers at Mass General Brigham have discovered a key mutation that may be a driving factor in resistance to certain drugs used to treat cancer.

Dejan juricTherapies investigational cancer therapeutics programTermeer centerCancer centerBoston based mass general brighamTargeted therapiesInvestigational cancer therapeutics programMass general cancerBreast cancerIk3ca geneRug bindingTermeer centerTargeted therapiesInvestigational cancer therapeutics