Kanazawa University research: Color coding molecular mirror images finanznachrichten.de - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from finanznachrichten.de Daily Mail and Mail on Sunday newspapers.
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KANAZAWA, Japan, July 14, 2021 /PRNewswire/ Researchers at Kanazawa University report in
Proceedings of the National Academy of Sciences how a protein molecular motor can chop off a piece of cell membrane. The constrict-and-cut mechanism resembles that of a ratchet motor, and is of importance in processes mediating the entry of particles into cells.
Cells in the human body constantly receive substances from the outside via a process called endocytosis. One important endocytosis pathway involves the formation of a protrusion within the cell membrane, pointing to the inside of the cell, triggered when a molecule needing to get in reaches the membrane. The protrusion wraps and closes around the molecule, after which it is cut off, leaving the wrapped molecule (a so-called vesicle) inside the cell. A key role in the cutting-off mechanism is played by dynamin, a protein that can locally constrict cell membranes, and chop off bits. The precise constriction
Kanazawa University research: Regulators for extracellular vesicle production prnewswire.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from prnewswire.com Daily Mail and Mail on Sunday newspapers.
Kanazawa University research: Solvent effects of siloxanes on donor-acceptor interactions
KANAZAWA, Japan, May 11, 2021 /PRNewswire/
Researchers at Kanazawa University report in Chemical Communications how solvents influence the strength of donor-acceptor interactions. They found that silicone solvents, providing low compatibility, intensify donor-acceptor interactions between aromatic molecules compared to hydrocarbon solvents.
Aromatic donor-acceptor (D-A) interactions are a type of non-covalent bond between a donor (electron-rich) and an acceptor (electron-deficient) aromatic molecules. Aromatic molecules feature one or more rings with delocalized electrons. The aromatic D-A interactions are widely used for building supramolecular structures, which are assembly of molecules formed by non-covalent bonds like building blocks. The supramolecular structures have smart properties such as external stimuli-responsiveness and self-repairing. The stability and smart properties of
Researchers at Kanazawa University report in the
Journal of Physical Chemistry Letters how high-speed atomic force microscopy can be used for studying DNA wrapping processes. The technique enables visualizing the dynamics of DNA–protein interactions, which in certain cases resembles the motion of inchworms.
The genetic material of most organisms is carried by DNA, a complex organic molecule. DNA is very long for humans, the molecule is estimated to be about 2 m in length. In cells, DNA occurs in a densely packed form, with strands of the molecule coiled up in a complicated but efficient space-filling way. A key role in DNA s compactification is played by histones, structural-support proteins around which a part of a DNA molecule can wrap. The DNA–histone wrapping process is reversible the two molecules can unwrap and rewrap but little is known about the mechanisms at play. Now, by applying high-speed atomic-force microscopy (HS-AFM), Richard Wong and colleagu