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Sweet move: a modified sugar enhances antisense oligonucleotide safety and efficacy

Sweet move: a modified sugar enhances antisense oligonucleotide safety and efficacy
sciencedaily.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from sciencedaily.com Daily Mail and Mail on Sunday newspapers.

Takanori yokotaTaiki matsubayashiOsaka universityMolecular therapy nucleic acidsTokyo medicalDental university

Sugar Rush: New Chemical Modification Improves ASO Targeting of CNS

Sugar Rush: New Chemical Modification Improves ASO Targeting of CNS
genengnews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from genengnews.com Daily Mail and Mail on Sunday newspapers.

Takanori yokotaSatoshi obikaKotaro yoshiokaTaiki matsubayashiOsaka universityTokyo medicalDental universityMolecular therapy

New chemical modification improves effectiveness and safety of ASO therapy for CNS diseases

Diseases that affect the brain and spinal cord can be particularly devastating, and finding new and more effective ways to treat these conditions is an important goal for researchers and clinicians alike.

Takanori yokotaTaiki matsubayashiOsaka universityMolecular therapy nucleic acidsTokyo medicalDental university

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS disease

Researchers have found that a newly developed modified sugar increases the efficacy and safety of antisense oligonucleotides designed to treat central nervous system disease.

Taiki matsubayashiTakanori yokotaDepartment of neurologyOsaka universityNeurological scienceMolecular therapy nucleic acidsTokyo medicalDental universityMolecular therapy