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Sugar Rush: New Chemical Modification Improves ASO Targeting of CNS

Sugar Rush: New Chemical Modification Improves ASO Targeting of CNS
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Takanori yokotaSatoshi obikaKotaro yoshiokaTaiki matsubayashiOsaka universityTokyo medicalDental universityMolecular therapy

Study paves way for developing effective ASO therapies for brain diseases with fewer side effects

A promising therapy for a range of brain diseases involves antisense oligonucleotides (ASOs)-;specialized molecules that can modulate RNA and alter protein production-;directly injected into the cerebrospinal fluid, in the space around the brain and spinal cord.

Takanori yokotaChunyan jiaKotaro yoshiokaEmily hendersonNucleic acidsTokyo medicalDental universityIndustry focus

Researchers suggest promising, safe approaches for brain treatment

Antisense oligonucleotides (ASOs), specialised molecules that may regulate RNA and affect protein creation, are being injected directly into the cerebrospinal fluid, the region around the brain and spinal cord, as a prospective treatment for a variety of brain illnesses.

Takanori yokotaChunyan jiaKotaro yoshiokaMolecular therapy nucleic acidsTokyo medicalDental universityEws india

Investegate |The Oligonucleotide Therapeuti Announcements | The Oligonucleotide Therapeuti: The Oligonucleotide Therapeutics Society Celebrates Another Remarkable Annual Meeting

Investegate announcements from The Oligonucleotide Therapeuti, The Oligonucleotide Therapeutics Society Celebrates Another Remarkable Annual Meeting

Moderna covidAlex garantoAlanm gewirtzHassan fakihKotaro yoshiokaGeri beatyDepartment of chemistryRadboud university medical centerDepartment of neurologyMary ann liebert incMcgill universityOligonucleotide therapeutics societyAnnual meetingRare diseases sessionMemorial scholarshipNeurological science

The Oligonucleotide Therapeutics Society Celebrates Another

SAN DIEGO, Oct. 09, 2021 (GLOBE NEWSWIRE) The Oligonucleotide Therapeutics Society's 17th Annual Meeting was held virtually the second year in a row.

Moderna covidAlex garantoAlanm gewirtzHassan fakihKotaro yoshiokaGeri beatyDepartment of chemistryRadboud university medical centerDepartment of neurologyMary ann liebert incMcgill universityOligonucleotide therapeutics societyAnnual meetingRare diseases sessionMemorial scholarshipNeurological science