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GZ17-6 02 Effective in Killing Multiple Myeloma Cells, Other Benefits When Combined With Bortezomib

The combination of GZ17-6.02 and bortezomib reduced of HDAC, and as a result ATG13 phosphorylation was enhanced, BAK levels increased, and BCL-XL levels were reduced.

Vitalii vodolazskyiGenzada pharmaceuticals united states incImpact journalsStudy evaluatingPatients with advanced solid tumorsCombination with capecitabineGenzada pharmaceuticals united states

MEI Pharma to Present Design of Ongoing Clinical Study Evaluating ME-344 at ASCO GI Cancers Symposium 2024

MEI Pharma to Present Design of Ongoing Clinical Study Evaluating ME-344 at ASCO GI Cancers Symposium 2024
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Davida walseyPatrickm bolandPharma incAcademic gi cancer consortiumOngoing phaseStudy evaluatingMetastatic colorectal cancerCombination intendedCreate metabolic synthetic lethalityCancers symposiumRefractory metastatic colorectal cancerPacific timePrivate securities litigation reform act

FDA Gives Cancer Drug Updates, Prostate Cancer Trial Enrolls Patients

Last week, the FDA provided updates on two cancer therapies. In this episode, we discuss those decisions and more.

Drug administrationMetastatic cervicalBiologics license applicationManufacturing concernsMissed gastric cancer drugStudy evaluatingAdvanced prostateDrug showsDisease control rateCervical cancerProstate cancerGastric cancerWaldenstrom x27s macroglobulinemia

F Hoffmann-La Roche Ltd: Roche s inavolisib combination reduces the risk of disease progression by 57% in people with advanced hormone receptor-positive, HER2-negative breast cancer with a PIK3CA mutation

F Hoffmann-La Roche Ltd: Roche s inavolisib combination reduces the risk of disease progression by 57% in people with advanced hormone receptor-positive, HER2-negative breast cancer with a PIK3CA mutation
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San antonioUnited statesRebekka schnellSabine borngrSileia urechKarsten kleineBruno eschliStefan klotterBirgit masjostSimon goldsboroughNathalie altermattLoren kalmGerard tobinKirti pandeyLevi garrawayHead of global product development

Roche s inavolisib combination reduces the risk of disease progression by 57% in people with advanced hormone receptor-positive, HER2-negative breast cancer with a PIK3CA mutation | 08 12 23

Roche s inavolisib combination reduces the risk of disease progression by 57% in people with advanced hormone receptor-positive, HER2-negative breast cancer with a PIK3CA mutation | 08 12 23
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United statesSan antonioNathalie altermattRebekka schnellKirti pandeySimon goldsboroughLoren kalmLevi garrawaySileia urechKarsten kleineRoche groupNational cancer instituteEpidemiologyand ends result programHead of global product developmentAntonio breast cancer symposiumChief medical officer