Compared with their unaffected siblings and unrelated controls, children with autism harbor more copy number variants in genes that govern the circadian cycle or are associated with insomnia.
Clinicians should consider ASD genetic screening in youths with a psychotic diagnosis due to the high genetic burden from rare copy number variants in both groups.
Clinicians should consider ASD genetic screening in youths with a psychotic diagnosis due to the high genetic burden from rare copy number variants in both groups.
Troves of sequencing data reveal genes tied to autism through different variant types, providing a more complete picture of the condition’s genetic roots and new clues to its heterogeneity.