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Key gene linked to male bias in autism, Tourette s, and ADHD uncovered

Sex bias in attention deficit hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and Tourette syndrome (TS).

United kingdomXgen exome research panelNature communicationsRarex linkedSimons simplex collectionAdolescent psychiatryAdolescent psychiatric assessmentHromosome xTourette syndromeX linked

Scientists Uncover The Roles Of Dozens Of Genetic Factors

Researchers identified dozens of genes that seem to cumulatively raise autism risks when mutated. Know more about the genetic factors behind this condition.

San franciscoUnited statesFroedtert health complete acquisitionAdvances in genomic researchUniversity of californiaAutism sequencing consortiumAutism researchOwnership of network healthAutism spectrum disorderGenomic researchNovo mutationsSimons simplex collectionSequencing consortiumFroedtert healthComplete acquisitionFull ownership

Some who lack autism diagnosis carry variants tied to the condition

The variants are associated with slight differences in measures of intelligence, income and employment, but the relationship may not be causal.

United kingdomFrance generalThomas bourgeronThomas rollandStephan sandersInstitut pasteurLundbeck foundation initiative for integrative psychiatric researchScientific researchUniversity of antwerpFrench national centerSimons foundationUniversity of oxfordHuman geneticsCognitive function unitSimons simplex collectionLundbeck foundation initiative

Partner selection may amplify rare variants in children

Nonrandom mating — the propensity for people to partner with others who share their traits — can increase the likelihood of autism or other conditions across…

United statesRenato polimantiSanthosh girirajanJohn constantinoYale universitySwedish national patient registerEmory university in atlantaPennsylvania state university in parkSimons foundationEmory universitySwedish national patientUnited kingdom biobankNorth americaSimons simplex collectionPennsylvania state universityUniversity park

Whole-genome trove ties new genes, variants to autism | Spectrum

A massive update to the MSSNG dataset gives qualified researchers ready access to explore autism’s genetic architecture on a cloud-based platform.

United statesUniversity of texas southwestern medical centerVicky garbuttMaria chahrourStephen schererBrett trostUniversity of torontoAmerican society of human geneticsSimons foundationAutism sequencing consortiumTexas southwestern medical centerSimons simplex collectionAmerican societyHuman genetics

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