Researchers produced the first molecular map of the genes that are active in the various cells of the human pancreas. They have also revealed differences in genetic activity between people with type 2 diabetes and healthy controls.
Single-cell RNA-sequencing (scRNA-seq) shows which genes are turned on in a cell and what their level of transcription is. This allows in-depth assessment of the biology of individual cells, and detection of changes that may indicate disease.
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