Probiotics could hold the answer to neurological issues, study suggests A new study in mice with social behaviour deficits has suggested the gut plays a lead role in behaviour and brain function and microbiome modulating products may hold the key to treatment of social neurological disorders.
Dr. Mauro Costa-Mattioli, professor and Cullen Foundation Endowed Chair in neuroscience and director of the Memory and Brain Research Center at Baylor College of Medicine, Texas, discovered with his team that different abnormal behaviours are interdependently regulated by the host s genes and microbiome.
The findings, published in the journal
Cell, reveal that in mouse models with neurodevelopmental disorders, hyperactivity is controlled by the host s genetics, whereas social behaviour deficits are mediated by the gut microbiome.
Gut Microbes Could be a Way to Treat Some Neurological Disorders
Researchers and clinicians have often studied genes that affect the function and development of the brain to explain neurological disorders. While we know that gene expression and variations in genetic sequences are important to human health, we re gaining a better appreciation of the influence of the gut microbiome on our biology. All of the microbes in the gut also have their own genomes, which affect us in different ways, and the gut also has a special, direct connection to the brain known as the gut-brain axis.
Researchers have now used a mouse model of behavioral problems to show how gut microbes may one day be a way to treat some neurological disorders. The work has been reported in
Probiotics could hold the answer to neurological issues, study suggests nutraingredients.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from nutraingredients.com Daily Mail and Mail on Sunday newspapers.
Microbes may hold the key for treating neurological disorders eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.