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Gut Microbiome May Provide Novel Therapies for Neurological Disorders Source: ChrisChrisW/Getty Images March 11, 2021 Researchers at the Baylor College of Medicine report that they have found that microbes in the gut may contribute to certain symptoms associated with complex neurological disorders. Their study “Dissecting the contribution of host genetics and the microbiome in complex behaviors,” published in Cell, also suggests that microbe-inspired therapies may one day help to treat them. Mauro Costa-Mattioli, PhD, professor and Cullen Foundation Endowed Chair in neuroscience and director of the Memory and Brain Research Center at Baylor, discovered with his team that different abnormal behaviors are interdependently regulated by the host’s genes and microbiome. Specifically, the team found that in mouse models for neurodevelopmental disorders, hyperactivity is controlled by the host’s genetics, whereas social behavior deficits are mediated by the gut microbiome.

Sean doolingMauro costa mattioliShelly buffingtonCullen foundationUniversity of texas medical branch in galvestonBaylor college of medicineBrain research center at baylorBaylor collegeCullen foundation endowed chairBrain research centerTexas medical branchசீன் டூலிங்மாரோ கோஸ்டா மததீொளிஷெல்லி பஃபிங்டன்கல்லன் அடித்தளம்பல்கலைக்கழகம் ஆஃப் டெக்சாஸ் மருத்துவ கிளை இல் கால்வெஸ்டன்