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Sex differences in brain in response to midlife stress linked to fetal stress exposures

Sex-related differences in the brain associated with depression, schizophrenia and bipolar disorder are related to maternal stress during fetal development. This finding points to the need to explore sex-dependent targets for early therapeutic intervention and prevention.

How we handle stress at 45 linked to prenatal exposure

Men and women whose mothers experienced stressful events during pregnancy regulate stress differently in the brain 45 years later, results of a long-term study demonstrate. In a unique sample of 40 men and 40 women followed from the womb into their mid-forties, the brain imaging study showed that exposure during fetal development to inflammation-promoting natural substances called cytokines, produced by mothers under negative stress, results in sex-associated differences in how the adult brain responds to negative stressful situations more than 45 years after birth, reports Jill M. Goldstein, founder and executive director of the Innovation Center on Sex Differences in Medicine  ) at Massachusetts General Hospital (MGH) and her co-authors.

Hardly any difference between brains of men, women: Study

ANI | Updated: Apr 03, 2021 18:15 IST Washington [US], April 3 (ANI): A team of researchers at the Rosalind Franklin University of Medicine and Science studied different research works on the differences between men and women s brains and concluded that the two brains are hardly different from one another. Men and women s brains do differ slightly, but the key finding is that these distinctions are due to brain size, not sex or gender, researcher Dr Eliot said. Sex differences in the brain are tiny and inconsistent, once individuals head size is accounted for. The unusually large study of studies, Dump the dimorphism : Comprehensive synthesis of human brain studies reveals few male-female differences beyond size, published in Neuroscience and Biobehavioral Reviews, finds that size is the only clear-cut difference between male and female brains.

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