Confirmation of Gene Mutation
For all 12
H. pylori strains used, the sequence of 16SrDNA, a ribosomal gene involved in protein production, was analyzed, and the presence or absence of gene mutation was examined. Table 3 shows the number of base substitutions and the number of deletions/insertions in the 16SrDNA sequence. Of these, susceptible strain 3 (S3), amoxicillin-resistant strain 1 (AC1), amoxicillin-resistant strain 2 (AC2), clarithromycin-resistant strain 1 (CH1), and metronidazole-resistant strain 2 (MZ2) were resistant to disulfiram in the growth suppression test. Strains resistant to disulfiram tended to have fewer base deletions/insertions.
Table 3 16S rDNA Sequence
Discussion
Eradication therapy using amoxicillin and clarithromycin is performed for
13–15 Calycosin is a fat-soluble component in the dried root of
Astragalus membranaceus, which are organic compounds widely found in nature. Calycosin exerts various anti-tumor activities in vitro and in vivo,
16–18 but its mechanism of action in human GC cells is not clear.
In this study, we evaluated the effects of calycosin on apoptosis, the cell cycle, and migration of GC cells under ROS regulation. In addition, we also determined the roles of MAPK/STAT3/NF-κB pathways in these processes.
Materials and Methods
Cell Lines and Cell Culture
Twelve types of GC cells (AGS, KATO-3, MKN-28, MKN-45, NCI-N87, SNU-5, SNU-216, SNU-484, SNU-668, YCC-1, YCC-6, and YCC-16) and normal human lung cells IMR-90 were purchased from American Type Culture Collection (Manassas, VA, USA), and three normal cell lines (GES-1, L-02, and 293T) were purchased from Saiqi Biotech Co., Ltd (Shanghai, China). AGS, KATO-3, MKN-28, MKN-45, SNU-5, SNU-216, SNU-484, SNU-668, IMR-90, and L-02 cells were
Dodecanol Market Forecast to Reach $700 Million by 2025 The Growing Personal and Household Care Industry Also Drive the Demand for Dodecanol Market
BriefingWire.com, 4/08/2021 - Dodecanol Market is forecast to reach $700 million by 2025, after growing at a CAGR of 5.2% during 2020-2025. Dodecanol is a saturated fatty alcohol with a sweet odor. It is an intermediate substance for the production of Dodecyl ethoxylates and Dodecyl sulfate salts. Surging use of dodecanol in automotive industries as fuel additives and lubricating oil formulation boosts the growth of Dodecanol market share. Furthermore, the growing personal and household care industry also drive the demand for Dodecanol, which in turn propels the market growth. Moreover, increasing demand from healthcare industries for disinfectants and cleaning products further augments the growth of Dodecanol market size.
The forecast involves key details on market size, market share, statistics, application, and revenue.
BriefingWire.com, 3/01/2021 - The Global Nafion Market 2020-2028 Report provides an in-depth analysis on the studied market that helps to seem at the longer term requirement also as prediction. The nafion market Report evaluates the market by key market players, opportunities, value, trends, growth, market share, market competition landscape, recent developments and sales volume analysis. Additionally, it magnifies the chance for decision-making and helps create an efficient counter-strategy to realize a competitive advantage. The report provides up-to-date review of the present global market scenario, the newest developments and drivers, and therefore the overall market environment is given within the study.
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The study on the global Mercaptopropionic Acid Market provides granular assessments of key growth dynamics and opportunities in the market. These include a comprehensive analysis of the regulatory and strategic landscape during the historical period on the global level and across numerous regions. Future Market Insights offers data-driven insights through the Mercaptopropionic Acid Market sizing and projections of various segments shares and size during the forecast period. The insights offered in the report are aimed at guiding companies and players to identify new growth avenues, winning imperatives, and untapped regional markets.
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