Systemic lupus erythematosus (SLE) is a severe multisystem autoimmune disease that can cause injury in almost every body system. While considered a classic example of autoimmunity, it is still relatively poorly understood. Treatment with immunosuppressive agents is challenging, as many agents are relatively non-specific, and the underlying disease is characterized by unpredictable flares and remissions. This State of The Art Review provides a comprehensive current summary of systemic lupus erythematosus based on recent literature. In basic and translational science, this summary includes the current state of genetics, epigenetics, differences by ancestry, and updates about the molecular and immunological pathogenesis of systemic lupus erythematosus. In clinical science, the summary includes updates in diagnosis and classification, clinical features and subphenotypes, and current guidelines and strategies for treatment. The paper also provides a comprehensive review of the large number
While there s no cure for lupus and treatments don t work for everyone with the disease, a new study shows a cancer therapy may kick hard-to-treat lupus into remission.
In Small Study, CAR-T Therapy Pushes Lupus Into Remission kulr8.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from kulr8.com Daily Mail and Mail on Sunday newspapers.
/PRNewswire/ Hospital for Special Surgery (HSS), the world s leading academic medical center specialized in rheumatic and musculoskeletal diseases, today.