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Transcripts For KPIX CBS 20240702

with so much darkness around us, our job is to light our candles and to bring light into this world. norah: weekend storm threat. the weather system that flooded the west heads east. medical breakthrough? the fda approves a cutting-edge gene editing therapy to be used in humans. did anybody use the word cure ? um. we do. [laughter] norah: we are on the road to tell the story of a frugal man making a difference after his death. forever changed because of his choice of how he lived. norah: good evening to our viewers in the west. and thank you for being with us on this friday night. you want to begin tonight with a very serious criminal charges facing the president s son, hunter biden. the indictment coming down last night is breathtaking in its scope, about how the yale trained lawyer allegedly spent years scheming to avoid more than a million dollars in taxes while in the words of prosecutors, living an extravagant lifestyle. the 56-page indictment in

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New Gene-Editing Treatments, Explained

FDA approves first use of CRISPR gene editing to treat sickle cell disease

The Food and Drug Administration (FDA) on Friday approved a new therapy for treating sickle cell disease, marking the first instance of CRISPR gene editing receiving approval from federal regulators. The FDA approved on Friday two new treatments for sickle cell disease (SCD): Casgevy and Lyfgenia. Casgevy, also known as exa-cel, is developed through a…

CRISPR-Cas9 promoting fetal hemoglobin production improves severe sickle cell disease

1. In this randomized controlled trial, infusion of OTQ923 disrupted inhibitory HBG1 and HBG2 promoter regions of the gamma-globin gene. 2. This disruption resulted in sustained production of fetal hemoglobin and improved symptoms of severe sickle cell disease (SCD). Evidence Rating Level: 2 (Good) Study Rundown: SCD is caused by mutations disrupting the function of

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