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Base editing can be preferable in curing sickle cell disease: Study

Base editing can be preferable in curing sickle cell disease: Study
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New yorkUnited statesDavid liuMitchell weissRichard merkinJude children research hospitalProfessor at broad instituteBroad instituteJude department of hematologyNature geneticsJude childrenResearch hospitalJonathan yenJude therapeutic genome engineeringTherapeutic genome engineeringJude department

Base editing shows potential superiority for

Adenosine base editing restarted fetal hemoglobin expression in cells from patients with sickle cell disease. Find how St. Jude & Broad are advancing to a cure.

United statesYong chengYoonjeong jangJingjing chenYu yaoRachel levineSenthil velan bhoopalanRuopeng fengMitchell weissDavid liuJohn tisdaleYichao liShondra pruett millerAkshay sharmaHenry bellThiyagaraj mayuranathan

Base editing shows promise for treating sickle cell disease and beta thalassemia

Gene therapy that alters hemoglobin genes may be an answer to curing sickle cell disease (SCD) and beta thalassemia.

United statesLily ramseySenthil velan bhoopalanCicera lazzarottoGuolian kangYong chengPhillip doerflerErin dempseyMitchell weissGregory newbyRuopeng fengYu yaoRachel levineJingjing zhangShengdar tsaiHenry bell

Base Editing Demonstrates Superiority in Curing Sickle Cell Disease

Base Editing Demonstrates Superiority in Curing Sickle Cell Disease
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David liuRichard merkinMitchell weissJude children research hospitalJude department of hematologyBroad instituteJude childrenResearch hospitalJonathan yenJude therapeutic genome engineeringTherapeutic genome engineeringJude department

Base editing shows potential superiority for curing sickle cell disease

Base editing shows potential superiority for curing sickle cell disease
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Richard merkinJohn tisdaleMitchell weissDavid liuNational heartBlood instituteProfessor at broad instituteJude department of hematologyMolecular therapeutics branchJonathan yenJude therapeutic genome engineeringTherapeutic genome engineeringJude departmentBroad institute