Greater manchester into tighter restrictions. Flown to london the conjoined twins from pakistan finally go home after their extraordinary treatment at great ormond street. How cold water swimmers are helping scientists working on a possible cure for dementia. And wasps are stung by four more positive coronavirus tests putting their premiership final against exeter on saturday in jeopardy. Good evening and welcome to bbc news. Wales will go into a two Week National lockdown from friday. The first minister, mark drakeford, said he was imposing the firebreak with a heavy heart. But he insisted that the sharp and deep measures were necessary in order to regain control of the virus and to prevent the nhs from becoming overwhelmed. The decision has sparked anger in some parts of wales where the number of cases is still low. The lockdown will last two weeks. It starts at 6pm this friday. Everyone must stay at home unless they are a key worker or cannot work from home. Mixing with other househ