Usual interstitial pneumonia (UIP) is characterised by a distinctive morphological
and radiological appearance that was considered the pathognomonic hallmark of idiopathic
pulmonary fibrosis (IPF). However, this peculiar lung remodelling pattern is also
seen in other fibrotic interstitial lung diseases, including hypersensitivity pneumonitis,
and connective tissue diseases. In this Personal View, we advocate the designation
of a UIP pattern as a single, discrete diagnostic entity, amalgamating its primary
form and secondary processes in disorders such as hypersensitivity pneumonitis (hypersensitivity
pneumonitis with UIP), rheumatoid arthritis (rheumatoid arthritis with UIP), and others.
Pulmonary graft-versus-host disease and chronic lung allograft dysfunction: two sides of the same coin?
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Pathogenesis of chronic obstructive pulmonary disease: understanding the contributions of gene–environment interactions across the lifespan
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Early Th2 inflammation in the upper respiratory mucosa as a predictor of severe COVID-19 and modulation by early treatment with inhaled corticosteroids: a mechanistic analysis
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Medicinal licensing of e-cigarettes
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