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Continued Treatment With Tirzepatide for Maintenance of Weight Reduction in Adults With Obesity: The SURMOUNT-4 Randomized Clinical Trial | Cardiology | JAMA

This randomized clinical trial examines the effect of tirzepatide on the maintenance of weight reduction.

Eteläuomen läiNew yorkUnited statesUnited kingdomLouisj aronneSenda biosciencesMedtech epitomeeEli lillyBausch health canadaGroup informationBoehringer ingelheimNovo nordiskHealth surveyAbbott laboratoriesWeight control centerEuropean association for study of diabetes

Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection

This randomized clinical trial compares the use of cefepime vs piperacillin-tazobactam and the risk of acute kidney injury and neurological dysfunction in adult

South koreaUnited statesChristopher seymourEdwardt qianNational institutes of healthNational heartBristol myers squibbTranslational sciencesPragmatic critical care research groupPediatric infectious diseases societySociety of infectious diseases pharmacistsMedicine associationEastern association for surgery of traumaAmerican society of parenteralDrug administrationR foundation for statistical computing

Two-Year Outcomes After Minimally Invasive Surfactant Therapy in Preterm Infants

This follow-up study of a randomized clinical trial examines the effect of minimally invasive surfactant therapy, surfactant administration via a thin catheter,

United statesUnited kingdomNew zealandNew south walesPetera dargavilleKanmaz kutmanChiesi farmaceuticiDepartment of paediatricsRoyal hobart hospital research foundationUniversity of sydneyUniversity of tasmaniaStata statistical softwareResearch councilToddler developmentAustralian national healthGroup information

Association of Menopausal Hormone Therapy With Breast Cancer Incidence and Mortality During Long-term Follow-up of the Women s Health Initiative Randomized Clinical Trials | Breast Cancer | JAMA

This study reports 20-year breast cancer incidence among participants in Women’s Health Initiative (WHI) trials randomized to conjugated equine estrogen (CEE) a

National institutes of healthUnited statesUniversity of arizonaFred hutchinson cancer research centerSan antonioMarcial stefanickJoan mcgowanCharles kooperbergRebecca jacksonMarian limacherAstra zenecaJoanne mansonShari ludlumNancy gellerMark espelandJacques rossouw

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