This review of the Women’s Health Initiative (WHI) summarizes the results of the 4 WHI clinical trials on menopausal hormone therapy, calcium plus vitamin
This study reports 20-year breast cancer incidence among participants in Women’s Health Initiative (WHI) trials randomized to conjugated equine estrogen (CEE) a
Women’s Health Initiative continues on at Fred Hutch
Nearly 30 years after its launch, the WHI and its data are still going strong, producing key findings February 24, 2021 • By Diane Mapes / Fred Hutch News Service Nearly 30 years after its launch, the Women s Health Initiative still has over 60,000 actively involved participants, some of them in their 100s. WHI was created to answer key questions about women s health, particularly after age 50. Stock photo by Getty Images
It started in 1992 with over $600 million worth of National Institutes of Health funding, 40 research centers, 161,000-plus study participants and big plans. Nearly 30 years later, the Women’s Health Initiative is still going strong with over 60,000 actively involved participants some centenarians and an economic return estimated at over $37 billion.
Democratizing DNA-based health risk scores
Hutch-led consortium receives $9.8M grant to improve genetic risk prediction for cardiovascular disease in racially and ethnically diverse populations December 10, 2020 • By Diane Mapes / Fred Hutch News Service Photo illustration by Getty Images
For more than a decade, scientists with the PAGE consortium (Population Architecture using Genomics and Epidemiology) have been focused on developing polygenic risk scores those statistical estimates of a person’s risk for disease based on their genes that will accurately predict risk in all major racial and ethnic groups in the U.S.
This is crucial since the Human Genome Project and a lot of the of genetic research done since has focused almost exclusively on people of European ancestry. As a result, polygenic risk scores designed to help clinicians and the general population gauge their susceptibility to various diseases aren’t