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NanoMosaic Demonstrates Robust Aptamer Performance for Protein Quantitation on the Company s Tessie™ System

/PRNewswire/ NanoMosaic, the pioneer and leader in nanoneedle (MosaicNeedle™) detection for proteomics and genomics applications has demonstrated.

Anesthetic may affect tau spread in the brain to promote Alzheimer s disease pathology

 E-Mail BOSTON - During the development and progression of Alzheimer s disease, a protein called tau accumulates and spreads in the brain. Understanding the mechanisms behind tau spread and its consequences may point to new prevention and treatment strategies for Alzheimer s disease and other forms of dementia. New insights now come from research that was led by investigators at Massachusetts General Hospital (MGH) and involves an anesthetic known to affect cognitive function. The findings are published in The scientists note that inflammation plays an important role in Alzheimer s disease, and microglia immune cells that reside in the brain are thought to be involved in this process by producing an inflammatory molecule called interleukin-6. To see if tau stimulates microglia to drive the development of Alzheimer s disease pathology, the MGH investigators and their colleagues conducted experiments with an inhaled anesthetic called sevoflurane. Their previous work showed that sev

Anesthetic may affect tau spread in the brain to promote Alzheimer s disease pathology

 E-Mail BOSTON - During the development and progression of Alzheimer s disease, a protein called tau accumulates and spreads in the brain. Understanding the mechanisms behind tau spread and its consequences may point to new prevention and treatment strategies for Alzheimer s disease and other forms of dementia. New insights now come from research that was led by investigators at Massachusetts General Hospital (MGH) and involves an anesthetic known to affect cognitive function. The findings are published in The scientists note that inflammation plays an important role in Alzheimer s disease, and microglia immune cells that reside in the brain are thought to be involved in this process by producing an inflammatory molecule called interleukin-6. To see if tau stimulates microglia to drive the development of Alzheimer s disease pathology, the MGH investigators and their colleagues conducted experiments with an inhaled anesthetic called sevoflurane. Their previous work showed that sev

NanoMosaic Announces Beta Placement of its Tessie™ System at Massachusetts General Hospital to Run Clinical Samples

Share: BOSTON, Dec. 16, 2020 /PRNewswire/  NanoMosaic has developed a streamlined platform with novel physical structures, MosaicNeedles™, to enable enhanced-generation digital protein interrogation. The Tessie™ platform  eliminates the bottleneck of beads, used for protein capture and labeling, and the limitations associated with them. The novel MosaicNeedle™ structures enable the unlabeled digital quantitation of proteins and nucleic acids across seven orders of dynamic range with high sensitivity. NanoMosaic first Tessie™ beta placement at Massachusetts General Hospital. The company announced that the first Tessie™ beta placement at Massachusetts General Hospital (MGH), within the lab of Dr. Zhongcong Xie, Henry Knowles Beecher Professor of Anesthesia at Harvard Medical School and Director of Biological Biomarker Consultation Unit at Massachusetts General Hospital will be used by MGH researchers to develop a panel of markers for the study of postoperative delirium

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