Collins and other and i age leaders testify before House Appropriations subcommittee on funding and research efforts. This is about 21 2 hours. The subcommittee will come to order. Thank you very much and apologize for being late. They take on a life of their own. I wanted to say good morning, welcome back to labor hhs, appropriations subcommittee. Let me say thank you on behalf of of the subcommittee for hosting members of the subcommittee for the site visit at the nih campus last week. We had a wonderful opportunity to learn more about nihs work, we learned about researchers working to develop treatments for major depression, shrinkage free cancer tumors in children, we heard from participants whose lives have been changed by Clinical Trials so it was a moving and informative experience. Let me welcome our witnesses including the five Institute Center directors who joined us today and in addition, always a great addition doctor Francis Collins, director of the National Institute of h