Pre-eclampsia test roll-out delayed by lack of funding pressandjournal.co.uk - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from pressandjournal.co.uk Daily Mail and Mail on Sunday newspapers.
Tyesha Kinnard was the first woman in America to receive the FDA-approved preeclampsia test. The results of that test proved she was amid severe preeclampsia and at risk of losing her life and the life of her baby.
One of the most influential charities working to make pregnancy safer today asks why Scots women are still not being offered cheap and effective life-saving tests available elsewhere in the UK.
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1Division of Cardiovascular Disease, Department of Medicine, The University of Alabama at Birmingham, Birmingham, AL, United States
2Molecular and Cellular Pathology, Department of Pathology, The University of Alabama at Birmingham, Birmingham, AL, United States
3Department of Biomedical Engineering, The University of Alabama at Birmingham, Birmingham, AL, United States
4Center for Translational Medicine, Temple University, Philadelphia, PA, United States
Background: Endothelial cells (ECs) play a critical role in the maintenance of vascular homeostasis and in heart function. It was shown that activated fibroblast-derived exosomes impair cardiomyocyte function in hypertrophic heart, but their effect on ECs is not yet clear. Thus, we hypothesized that activated cardiac fibroblast-derived exosomes (FB-Exo) mediate EC dysfunction, and therefore modulation of FB-exosomal contents may improve endothelial function.