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Researchers discover SARS-CoV-2 inhibitors
E-Mail IMAGE: with one of the newly developed inhibitors in the active centre. The individual domains of the protein are shown in different colours, the inhibitor in pink. view more Credit: © V. Namasivayam/Pharmazeutisches Institut/Uni Bonn A research team of pharmacists at the University of Bonn has discovered two families of active substances that can block the replication of the SARS-CoV-2 coronavirus. The drug candidates are able to switch off the the key enzyme of the virus, the so-called main protease. The study is based on laboratory experiments. Extensive clinical trials are still required for their further development as therapeutic drugs. The results have now been published in the journal
Nordrhein westfalen
Vigneshwaran namasivayam
Katharina sylvester
Dominik thimm
Ghazl al hamwi
Christin vielmuth
Jochen bodem
Vittoria lopez
Salahuddin mirza
Thanigaimalai pillaiyar
Carina lemke
Angewandte chemie
Robin gedschold
Maria zyulina
Phuong vu
Julian breidenbach
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