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Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial

Molnupiravir did not reduce the frequency of COVID-19-associated hospitalisations or death among high-risk vaccinated adults in the community.

City ofUnited kingdomNorthern irelandYusuf soniJulianne brownMike butlerOlajide popoolaGreg irvingDivya shahAfsana safaJames kennardSarit ghoshSatash sehdevOmair razzaqUmar khanScot richardson

Deaths from alcohol-related liver disease in the UK: an escalating tragedy

In 2013, the UK National Confidential Enquiry into Patient Outcome and Death (NCEPOD) published Measuring the Units.1 This report on UK hospital deaths from alcohol-related liver disease in 2011 highlighted the avoidable nature of many of these deaths and found that care was less than good in more than half of the cases reviewed; basic omissions in patient care and missed opportunities were common, including the identification of patients with decompensated liver disease and initiation of simple urgent investigation and treatment.

United kingdomAlikhon alievGastroenterol hepatolNational confidential enquiryLancet standing commission on liver diseaseBritish society of gastroenterologyLancet commissionOffice for health improvementOffice for national statisticsConfidential enquiryPatient outcomeHealth improvementPharmacol therLancet standing commissionLiver diseaseClin exp res

Hepatocellular carcinoma

Hepatocellular carcinoma
thelancet.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from thelancet.com Daily Mail and Mail on Sunday newspapers.

United statesUnited kingdomSri lankaSouth koreaMiaoli xianDavey smithClin gastroenterol hepatolLe cleachJ clin gastroenterolGastroenterol hepatolVietti violiWorld health organizationInternational consensus group for hepatocellular neoplasiaInternational liver cancer associationCancer statisticsClin oncol

The effect of azithromycin on structural lung disease in infants with cystic fibrosis (COMBAT CF): a phase 3, randomised, double-blind, placebo-controlled clinical trial

The effect of azithromycin on structural lung disease in infants with cystic fibrosis (COMBAT CF): a phase 3, randomised, double-blind, placebo-controlled clinical trial
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United statesEsther jrPediatr pulmonolJ clin pharmacolInstitute for clinicalTransl medEnglj medCyst fibrosPharmacol therDatabase syst revRespir medEconomic reviewOpin pediatr
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