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Nobel-winning bodily pressure sensors filmed for first time
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Imperial Films Nobel-Winning Bodily Pressure Sensors for First Time
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Biodegradable Nanoprobes Improve Cancer Diagnosis
Written by AZoNanoMar 12 2021
New nanoprobes, which were recently developed by Imperial College London (ICL) and tested in zebrafish, could help identify cancer more precisely and may support the diagnosis and treatment in the days to come.
Purple cancer cells are labeled using bioharmonophores (white label). Image Credit: Imperial College London.
To clearly visualize tumors in the body for cancer diagnosis, physicians can utilize miniature optical probes (nanoprobes) that illuminate upon binding to tumors. Such nanoprobes enable doctors to detect the size, shape and location of tumors in the body.
The majority of the nanoprobes are fluorescent, which means they absorb light of a particular color, such as blue, and then produce a background light of a different color, such as green.
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To highlight tumours in the body for cancer diagnosis, doctors can use tiny optical probes (nanoprobes) that light up when they attach to tumours. These nanoprobes allow doctors to detect the location, shape and size of cancers in the body.
Most nanoprobes are fluorescent; they absorb light of a specific colour, like blue and then emit back light of a different colour, like green. However, as tissues of the human body can emit light as well, distinguishing the nanoprobe light from the background light can be tough and could lead to the wrong interpretation.
Now, researchers at Imperial College London have developed new nanoprobes, named bioharmonophores and patented at Imperial, which emit light with a new type of glowing technology known as second harmonic generation (SHG).
New biodegradable nanoprobes could help detect cancer more accurately
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