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Study reveals genetic chain reaction that drives the spread of prostate cancer

RICHMOND, Va. — New research from scientists at VCU Massey Comprehensive Cancer Center and the VCU Institute of Molecular Medicine (VIMM) determined that a particular gene — MDA-9/Syntenin-1/SDCBP — is

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VCU scientists discover gene behind events that lead to prostate cancer growth and metastasis

VCU scientists discover gene behind events that lead to prostate cancer growth and metastasis
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Paulb fisherSwadeshk dasThelma newmeyer cormanMassey comprehensive cancer centerProceedings of the national academy sciencesCancer research at masseyDepartment of humanNational foundation for cancer researchCancer center support grantSchool of medicineNational cancer instituteInstitute of molecular medicineComprehensive cancer centerMolecular medicineNational academyThelma newmeyer corman endowed chair

Study reveals genetic chain reaction that drives the spread of prostate cancer

Study reveals genetic chain reaction that drives the spread of prostate cancer
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Thelma newmeyer cormanSantanu majiSwadeshk dasPaulb fisherDepartment of humanProceedings of the national academy sciencesSchool of medicineCancer research at masseyMassey comprehensive cancer centerInstitute of molecular medicineComprehensive cancer centerMolecular medicineNational academyThelma newmeyer corman endowed chairCancer researchMolecular genetics

T Cells Engineered To Attack a Variety of Cancers

Control mice (left panel) with prostate cancer show large areas of metastasis in the lungs (blue). When a subset of animals were treated with unmodified T cells (middle panel), the secondary tumors were smaller than in untreated mice. And when a separate group of mice received T cells engineered to produce MDA-7/IL-24 (right panel), metastases shrunk even more, in some cases down to nothing. Credit: Shawn Wang, PhD Read Time: Through T cell engineering, researchers at Virginia Commonwealth University Massey Cancer Center show that it s possible to arrest tumor growth for a variety of cancers and squash the spread of cancer to other tissues. This research will be published in tomorrow s print edition of Cancer Research.

Xiang yang shawn wangThelma newmeyer cormanPaulb fisherCancer researchVirginia commonwealth university massey cancer centerSchool of medicineNational cancer instituteInstitute of molecular medicineDepartment of humanOncology researchCancer biologyDevelopmental therapeuticsMolecular geneticsMolecular medicineThelma newmeyer corman endowed chairJudy wason distinguished professorship

Study focuses on engineering T cells to attack cancer broadly

Study focuses on engineering T cells to attack cancer broadly ANI | Updated: May 01, 2021 08:27 IST Richmond (Virginia) [United States], May 1 (ANI): Through T cell engineering, researchers at Virginia Commonwealth University Massey Cancer Center show that it s possible to arrest tumour growth for a variety of cancers and squash the spread of cancer to other tissues. This research will be published in the journal Cancer Research. The paper builds on decades of research by study co-senior author Paul B. Fisher, M.Ph., Ph.D., a member of Massey s Cancer Biology research program, who discovered a protein called IL-24 that attacks a variety of cancers in several different ways.

Virginia commonwealth university massey cancer centerUnited statesXiang yang shawn wangThelma newmeyer cormanPaulb fisherCancer researchSchool of medicineNational cancer instituteInstitute of molecular medicineDepartment of humanOncology researchCancer biologyDevelopmental therapeuticsMolecular geneticsMolecular medicineThelma newmeyer corman endowed chair