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<p><strong>The loss-of-function mutation of <em>KMT2C</em>, a gene involved in histone modification, leads to the development of autism and other neurodevelopmental deficits. However, the precise mechanism of the disease progression is still unknown. Now, researchers from Japan have developed an animal model and elucidated the mechanism by which mutation in genes involved in chromatin modification causes autism. They have also discovered a drug that can be used in the treatment of autism.</strong></p>

Japan generalShigehiro kurakuTadafumi katoKurara hondaTakumi nakamuraAtsushi takataJunko uedaTakashi tsuboiMizuho ishiwataToru takumiTomonori haraShigeyoshi itoharaToru yoshiharaTakaoki kasaharaChiharu tanegashimaYuki kobayashi