Results have potential applications to cut risk of age-related degenerative diseases
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BOSTON (December 15, 2020)-A protein that functions like the vintage video game Pac-Man, eating toxic cellular waste caused by high sugar intake, is itself compromised by a sugary diet, according to the results of a study in mice with potential implications for humans. The study, led by a research team at Tufts University joined by researchers at eight other institutions, appears in Aging Cell.
The protein alleviates age-related cellular damage stemming from too much sugar consumption, according to the study findings. “This is a ‘double jeopardy’ impact. On one hand, proteins are damaged by excess sugars and must be removed to avoid toxic effects on cells. On the other hand, the very protein that works to remove and repair our cells from a high sugar diet is itself vulnerable to sugar, leaving cells threatened,” said Allen Taylor, co-last author and lead scientist at the
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The Internet of Things (IoT) has ushered in a new era, with everyday items evolving into what we now refer to as cyber-physical systems. These systems are physical mechanisms controlled or monitored by computer algorithms and deeply intertwined through the internet. Such systems have pierced their way into industry and are being deployed and used above all to manage and control industrial processes, thus giving rise to the so-called Industry 4.0. ICREA research professor Jordi Cabot and researcher Abel Gómez, two members of the Systems, Software and Models (SOM) Research Lab at the Universitat Oberta de Catalunya (UOC) Internet Interdisciplinary Institute (IN3), in collaboration with the IKERLAN technology research centre, have designed an innovative new tool for automating and streamlining the creation of systems that employ asynchronous event-driven communication, one of the most widely used computer architectures in this sector. The tool is the first to use the recently