Bionano Publishes Method for Identifying Genes Likely to Cause Neurological Diseases Based on a Model Developed by Lineagen to Improve Interpretation of Variants of Unknown Significance Proprietary scoring algorithm may help identify novel genes for nervous system disorders; applications include patient testing and eventually discovery research with Saphyr
February 22, 2021 08:00 ET | Source: Bionano Genomics Bionano Genomics San Diego, California, UNITED STATES
SAN DIEGO, Feb. 22, 2021 (GLOBE NEWSWIRE) Bionano Genomics, Inc. (Nasdaq: BNGO) announced the publication of a study by its Lineagen team that describes the first genome-wide model to assess and score nearly all protein-coding genes based on their likelihood to cause central nervous system (CNS) disease. The resulting list of high scoring genes enhances Lineagen’s clinical interpretation capabilities allowing their genetic counsellors to better interp
Day Five of Bionano’s Next-Generation Cytogenomics Symposium: Saphyr Identifies Structural Variants that May Predispose to Severe COVID-19 Illness
January 18, 2021 19:00 ET | Source: Bionano Genomics Bionano Genomics San Diego, California, UNITED STATES
COVID-19 Host Genome Structural Variant (SV) Consortium used Saphyr to identify SVs in severe COVID-19 patients that affect genes involved in immunity, airway mucous, and viral replication
SVs found by several investigators point to a central role for disease severity of the interferon response pathway
Consortium has added investigators from Augusta University, Boston Children’s Hospital, New York Genome Center, Radboud University, Rockefeller University, UC San Diego, Virginia Commonwealth University, and two dozen other institutes from around the world
COVID-19 Host Genome SV Consortium Identifies Structural Variants with Possible Roles in Pathogenesis and Outcomes in Severely Ill COVID-19 Patients Using Bionano’s Saphyr® System First publication from international consortium highlights prowess of Saphyr in identifying large SVs with clinical significance and in COVID-19, an area with great public health implications
January 11, 2021 08:00 ET | Source: Bionano Genomics Bionano Genomics San Diego, California, UNITED STATES
SAN DIEGO, Jan. 11, 2021 (GLOBE NEWSWIRE) Bionano Genomics, Inc. (Nasdaq: BNGO), announced today the first publication from the COVID-19 Host Genome Structural Variant Consortium. The study found that optical genome mapping (OGM) with Bionano’s Saphyr System identified structural variants (SVs) that affect genes in pathways that control immune and inflammatory response, viral reproduction and mucosal function. The authors believe these S