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Model organisms are more than just monkeys and mice
Researchers use all kinds of living organisms to learn about life, from monkeys and mice to fruit flies and fungi even a relative of the mustard family that s celebrating its 200th anniversary. The list is legendary.
Model organisms or research organisms, as they are also known are living things that scientists, such as biologists, use to study human and other animal or plant life.
A model organism can be anything from single-celled bacteria to viruses and fungi. They can be more complex organisms, such as monkeys, mice, rats, frogs, elephants and a salamander called axolotl.
New compound may slow aging and age-related diseases
A compound that extends lifespan in a tiny nematode worm slows bone loss in aging mice. That surprising result comes from a longitudinal and functional study of 700 aging mice at the Buck Institute, a project that provides a treasure trove of data for researchers aiming to develop therapeutics to slow aging and age-related diseases.
The study is currently online in the
Journal of Bone and Mineral Research Plus.
The project, which involved five Buck labs and took several years to complete, involved serially profiling the individual mice as they aged while testing several therapeutics that extended lifespan in simple model organisms or reduced neurological disease in mice.