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Empagliflozin does not decrease risk of hospitalization or death after myocardial infarction

1. In this randomized controlled trial, empagliflozin was not shown to decrease the risk of hospitalization for heart failure or death among patients after acute myocardial infarction (MI). 2. Safety outcomes were generally similar between the empagliflozin and placebo groups. Evidence Rating Level: 1 (Excellent) Study Rundown: It is well-established that sodium-glucose cotransporter 2 (SGLT2)

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Resistance training not superior to neuromuscular exercises for hip osteoarthritis

Resistance training not superior to neuromuscular exercises for hip osteoarthritis
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Minute medicine incRating levelHip disabilityOsteoarthritis outcome score

Multivariate predictive model for bone marrow sampling in MGUS patients

1. A multivariate predictive model was developed to help determine when a bone marrow sample would help distinguish between patients with monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM). 2. The model aimed to minimize unnecessary bone marrow sampling in this population. Evidence Rating Level: 2 (Good) Study Rundown: MGUS may be

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Personalized therapy does not reduce hospitalization in chronic kidney disease

1. In this randomized controlled trial, algorithmic identification based on electronic health records (EHRs) and practice facilitators did not reduce hospitalization rates among patients with chronic kidney disease (CKD). 2. Among patients with an unknown ASCVD risk score, those deemed statin-eligible by the model were nearly twice as likely to have incident MACE. Evidence Rating

Minute medicine incRating levelConfidence interval

Medical cannabis use increased in the United States from 2020 to 2022

1. In this retrospective cohort study, enrollment in medical cannabis programs increased overall in the United States (US) between 2020 and 2022. 2. In jurisdictions with nonmedical adult-use laws, enrollment in medical access programs declined within this time frame. Evidence Rating Level: 2 (Good) Study Rundown: Despite the introduction and expansion of legal cannabis use

United statesMinute medicine incRating level