Celebrations like St. Patrick's Day and the start of NCAA March Madness can lead to overindulging and a heart condition with potentially dangerous effects.
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Patients with secondary mitral regurgitation (MR) who were left with high gradients after a MitraClip procedure were not inherently at a disadvantage in their subsequent clinical outcomes, according to a COAPT analysis.
MitraClip-treated trial participants, divided into quartiles by mitral valve gradient (MVG) on discharge, shared similar odds of combined all-cause mortality and heart failure hospitalization at 2 years (
P=0.78):
Q2 (3.0 mm Hg; n=61): 49.2%
Q3 (4.2 mm Hg; n=62): 40.6%
Q4 (7.2 mm Hg; n=64): 40.9%
These findings persisted after adjustment for baseline clinical and echocardiographic characteristics, post-procedure MR grade, and number of clips implanted, reported Howard Herrmann, MD, of the Hospital of the University of Pennsylvania in Philadelphia, and colleagues in