The human gut microbiome may provide a noninvasive prognostic tool for brain health measures, including cognitive function and some psychiatric states, says a new analysis from researchers in the U.S. and Korea.
The human gut microbiome may provide a noninvasive prognostic tool for brain health measures, including cognitive function and some psychiatric states, says a new analysis from researchers in the U.S. and Korea.
Obesity is a risk factor for cognitive dysfunction and neurodegenerative disease, including Alzheimer's disease (AD). The gut microbiota-brain axis is altered in obesity and linked to cognitive impairment and neurodegenerative disorders. Here, we targeted obesity-induced cognitive impairment by testing the impact of the probiotic Clostridium butyricum, which has previously shown beneficial effects on gut homeostasis and brain function. Firstly, we characterized and analyzed the gut microbial profiles of participants with obesity and the correlation between gut microbiota and cognitive scores. Then, using an obese mouse model induced by a Western-style diet (high-fat and fiber-deficient diet), the effects of Clostridium butyricum on the microbiota-gut-brain axis and hippocampal cognitive function were evaluated. Finally, fecal microbiota transplantation was performed to assess the functional link between Clostridium butyricum remodeling gut microbiota and hippocampal synaptic prote
Health Canada has authorized functional claims that Chr Hansen’s probiotic DDS-1 strain, “helps alleviate perceived stress and improve irritable bowel syndrome-related quality of life in adolescents and adults”.
Supplements containing a combination of Limosilactobacillus and Bifidobacterium probiotic strains may boost a new mother’s mood after delivery, says a new randomized, double-blind, controlled trial from Italy.