Ammonium Nitrate is a critical component of fertilizer, but over time it absorbs a lot of moisture and becomes dangerous. Near-infrared spectroscopy allows for the quick, accurate and easy determination of moisture content.
Utilizing Raman for Raw Material Verification and Identification
Image Credit: Metrohm AG
There is an important reason why raw material identification and verification (RMID) is a complicated process: it confirms the quality of the raw materials which are utilized in the manufacture of products that you put in and on your body.
The complexity of RMID spans the spectrum from the testing process to analytical methods and instruments, then to the governmental standards and norms which regulate all aspects of RMID, including electronic records, the extent of sampling, system suitability, method validation and many others.
With Mira P and Mira Cal P, Metrohm Raman simplifies RMID. Image Credit: Metrohm AG
Image Credit: Metrohm AG
Diet is vital for our health. There has been a growing interest in food additives and dietary supplements like prebiotics like β-galactooligosaccharides (GOSs) in the past few years. Establishing the total GOS contents in food and supplements is vital to fulfilling strict food safety and labeling requirements.
The most widely utilized technique for total GOS determination is based on enzymatic hydrolysis to break down the complex molecules into simple carbohydrates before their chromatographic analysis.
This article describes the benefits of utilizing an improvement to AOAC Method 2001.02 by employing ion chromatography with amperometric detection (IC-PAD) and full sample automation after enzymatic hydrolysis.
Recognizing the Endpoints of Automated Titrations
Image Credit: Metrohm AG
Many users gained their first practical titration experience during chemistry studies in school. A student would learn how to carry out a manual visual endpoint titration.
This was done by using a manual buret filled with titrant and adding each drop individually to an Erlenmeyer flask containing the sample solution (including the analyte to be measured) and the indicator, which was added before the titration.
Minutes pass with increasing uncertainty with each drop and even slight color change of the sample solution, and a student could wonder if they have already reached the true endpoint, whether to add another drop or if they have even over-titrated.
How To Convert From Manual to Automated Titration Procedures
Webinar gives best practice guidelines for modernizing pharmaceutical assay testing
Titration is an important analytical method that is widely used for pharmaceutical assay testing. However, even though such tests are nowadays mostly performed utilizing digital instrumentation and software, USP general chapter still refers to manual visual endpoint titration. Recently, also US Pharmacopoeia has published recommendations for converting manual titrations into automated titration procedures.
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This webinar takes place on 18th May 2021, 11:00 a.m. CEST
This webinar on May 18, 2021 will give attendees clear guidelines how to convert manual titration methods into automated titrations and how these methods can be validated. Attendees of this webinar will learn and know: