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BIOSTEMI at 2 Years: Orsiro Continues to Lower TLF in STEMI Patients

March 16, 2021 Between 1 and 2 years, the device-oriented advantage offered by an ultrathin-strut, biodegradable-polymer DES continues to accrue in patients treated for STEMI, the latest data from the BIOSTEMI trial show. At 2 years, the rate of target lesion failure was 5.1% with the sirolimus-eluting Orsiro stent (Biotronik) and 8.1% with the thin-strut, durable-polymer, everolimus-eluting Xience Xpedition/Alpine (Abbott) stent, Thomas Pilgrim, MD (Bern University Hospital, Switzerland), reported this weekend during the virtual CRT 2021 meeting. At 1 year, the rates were 4% and 6% respectively. “When we look at a landmark analysis with a time point at 1 year, we see actually that the difference still accrues over time,” senior investigator Juan F. Iglesias, MD (Geneva University Hospitals, Switzerland), told TCTMD. “The curves are still diverging,” which he said supports the idea that small differences in stent design can impact prognosis.

A Fresh Foray in the Salt Wars: Life Expectancy Higher With Greater Sodium Intake

December 24, 2020 Greater sodium intake on a national level is associated with a longer average life expectancy and reduced all-cause mortality, according to an ecological study based on data from 181 countries. But the meaning of these findings, which run counter to advice from international societies and organizations, remains unclear. After adjusting for countries’ gross domestic product and average body mass index, there was an increase of 2.6 years of healthy life expectancy at birth and an additional 0.3 years at age 60 for each additional gram of daily sodium intake, researchers led by Franz Messerli, MD (Bern University Hospital, Switzerland; Jagiellonian University, Krakow, Poland; and Icahn School of Medicine at Mount Sinai, New York, NY), report.

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