March 16, 2021
Between 1 and 2 years, the device-oriented advantage offered by an ultrathin-strut, biodegradable-polymer DES continues to accrue in patients treated for STEMI, the latest data from the BIOSTEMI trial show.
At 2 years, the rate of target lesion failure was 5.1% with the sirolimus-eluting Orsiro stent (Biotronik) and 8.1% with the thin-strut, durable-polymer, everolimus-eluting Xience Xpedition/Alpine (Abbott) stent, Thomas Pilgrim, MD (Bern University Hospital, Switzerland), reported this weekend during the virtual CRT 2021 meeting. At 1 year, the rates were 4% and 6% respectively.
“When we look at a landmark analysis with a time point at 1 year, we see actually that the difference still accrues over time,” senior investigator Juan F. Iglesias, MD (Geneva University Hospitals, Switzerland), told TCTMD. “The curves are still diverging,” which he said supports the idea that small differences in stent design can impact prognosis.