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Credit: Source: IFJ PAN Malignant tumour cells undergo mechanical deformation more easily than normal cells, allowing them to migrate throughout the body. The mechanical properties of prostate cancer cells treated with the most commonly used anti-cancer drugs have been investigated at the Institute of Nuclear Physics of the Polish Academy of Sciences in Cracow. According to the researchers, current drugs can be used more effectively and at lower doses. In cancer, a key factor contributing to the formation of metastasis is the ability of the neoplastic cells to undergo mechanical deformation. At the Institute of Nuclear Physics of the Polish Academy of Sciences (IFJ PAN) in Cracow, research on the mechanical properties of cells has been conducted for a quarter of a century. The latest study, carried out in cooperation with the Department of Medical Biochemistry of the Jagiellonian University Medical College, concerned several drugs currently used in prostate cancer chemotherapy, and

Malgorzata lekkaAndrzej kubiakMarian smoluchowski krakDepartment of cell biologyNational research centreResearch consortiumEuropean commissionDepartment of biophysical microstructuresInstitute of nuclear physicsBiotechnology of the jagiellonian universityHenryk niewodniczanski institute of nuclear physicsAcademy of sciencesCyclotron centre bronowiceUniversity of milan department physicsHr excellence in researchNuclear physics