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Discovery on housekeeping genetic elements reveals a novel avenue in cancer therapy

Technological advancements have enabled scientists to comprehensively explore genetic control elements, unraveling the complexities of gene activation mechanisms in our genetic code.

Kenta nakaiMartin lozaAlexis vandenbonLaboratory of functional analysisNucleic acids research onKyoto universityUniversity of tokyoInstitute of lifeInstitute of medical scienceMedical scienceFunctional analysisProfessor kenta nakaiAssistant professorAssociate professorMedical sciencesNucleic acids research

New study reveals crucial housekeeping genetic elements and their potent role to fight cancer

New study reveals crucial housekeeping genetic elements and their potent role to fight cancer
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Alexis vandenbonKenta nakaiMartin lozaKyoto universityNucleic acids research onLaboratory of functional analysisUniversity of tokyoInstitute of lifeInstitute of medical scienceFunctional analysisMedical scienceProfessor kenta nakaiAssistant professorAssociate professorMedical sciencesNucleic acids research

Research Unveils Key Genetic Elements in Cancer Battle

Research Unveils Key Genetic Elements in Cancer Battle
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Martin lozaKenta nakaiAlexis vandenbonLaboratory of functional analysisInstitute of medical scienceKyoto universityNucleic acids research onInstitute of lifeUniversity of tokyoFunctional analysisMedical scienceProfessor kenta nakaiAssistant professorAssociate professorMedical sciencesNucleic acids research

Study reveals crucial housekeeping genetic elements and their potential to fight cancer

Study reveals crucial housekeeping genetic elements and their potential to fight cancer
medicalxpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medicalxpress.com Daily Mail and Mail on Sunday newspapers.

Alexis vandenbonMartin lozaKenta nakaiUniversity of tokyoLaboratory of functional analysisKyoto universityNucleic acids researchInstitute of lifeInstitute of medical scienceNucleic acidsFunctional analysisMedical scienceProfessor kenta nakaiAssistant professorAssociate professorMedical sciences

New study reveals crucial housekeeping gene

<p style="text-align:justify"><strong>A recent study in genetic control elements revealed around 11,000 gene regulators active in every cell type, also known as housekeeping cis-regulatory elements (HK-CREs). These elements are vital in maintaining cellular stability beyond conventional gene regulation, influencing diverse cellular functions across healthy cell types. Moreover, a subset of these housekeeping elements, particularly those related to zinc finger genes, was found to have reduced activity in diverse cancers, suggesting their role as potential housekeeping tumor suppressors.</strong></p>

Martin lozaAlexis vandenbonKenta nakaiMethod of researchNucleic acids research onUniversity of tokyoKyoto universityLaboratory of functional analysisNucleic acids researchInstitute of medical scienceInstitute of lifeFunctional analysisMedical scienceProfessor kenta nakaiAssistant professorAssociate professor