Japan s early summer saury fishing expedition in the northern Pacific is expected to be skipped for a third year because of bad catches and increasing fears Russia could seize Japanese fishing boats amid tensions over Ukraine.
Japanese fishing boats usually sail within the zone extending 200 nautical miles, or 370 kilometers, from the Russian coastline to reach their saury fishing area.
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A Wyss Institute-led collaboration spanning four research labs and hundreds of miles has used the Institute s organ-on-a-chip (Organ Chip) technology to identify the antimalarial drug amodiaquine as a potent inhibitor of infection with SARS-CoV-2, the virus that causes COVID-19.
The Organ Chip-based drug testing ecosystem established by the collaboration greatly streamlines the process of evaluating the safety and efficacy of existing drugs for new medical applications, and provides a proof-of-concept for the use of Organ Chips to rapidly repurpose existing drugs for new medical applications, including future pandemics. The research is reported in
Nature Biomedical Engineering.
While many groups around the world have been testing existing drugs for efficacy against COVID-19 using cultured cells, it is well known that cells grown in a dish do not behave like the cells in a living human body, and many drugs that appear effective in lab studies do not work in patients. T