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Published:
7:22 PM January 10, 2021
Reporter Ben Jolley is undergoing Invisalign treatment with Dr Kishan Patel (pictured) at March Dental Surgery. This is how Ben s teeth have changed after just six weeks.
- Credit: MARCH DENTAL SURGERY
Reporter Ben Jolley talks about his ongoing teeth transformation that he is undertaking with Invisalign specialist Dr Kishan Patel at March Dental Surgery.
Near the end of 2020, I began my teeth transformation and I m happy to say that the process is - aside from the first few days - pain-free.
The fit, as Dr Patel warned me, is undoubtedly the worst part of it all. But as for the Invisalign itself, it’s extremely simple and very easy to use.
Wayne Lewis |
FINDINGS
Research led by scientists from UCLA and Harvard University has uncovered details about how the bacterium Clostridioides difficile causes excessive inflammation in the gut that can lead to potentially deadly colitis. Studying C. difficile toxin A, one of two toxins released by the bacterium, the researchers produced two key findings.
They pinpointed which part of the toxic protein can permeate cell membranes to gain entry to cellular structures called endosomes, demonstrating that even fragments of the protein that contain that key segment are capable of accessing endosomes.
In addition, they revealed how the toxin molecule causes inflammation, which has been a long-standing mystery because such molecules are generally quickly digested in the gut. The scientists found that toxin A and surprisingly even fragments of the toxin can organize DNA into ordered crystalline particles that amplify an immune response by binding to multiple TLR9 recept
New details about how bacterial toxins cause life-threatening colitis
January 8, 2021ScienceBlog.com
Research led by scientists from UCLA and Harvard University has uncovered details about how the bacterium Clostridioides difficile causes excessive inflammation in the gut that can lead to potentially deadly colitis. Studying C. difficile toxin A, one of two toxins released by the bacterium, the researchers produced two key findings.
They pinpointed which part of the toxic protein can permeate cell membranes to gain entry to cellular structures called endosomes, demonstrating that even fragments of the protein that contain that key segment are capable of accessing endosomes.
In addition, they revealed how the toxin molecule causes inflammation, which has been a long-standing mystery because such molecules are generally quickly digested in the gut. The scientists found that toxin A and surprisingly even fragments of the toxin can organize DNA into ordered crystalline particles
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