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Cureus | The Importance of the Thyroid Nodule Location in Determining the Risk of Malignancy: A Retrospective Study

Introduction Thyroid nodules are very common. However, the majority of thyroid nodules are benign. Ultrasound is the first-line imaging investigation of choice for thyroid nodules. Certain sonographic features are associated with an increased risk of malignancy. Recent studies suggested that the location of the nodule may be associated with the malignancy risk. Hence, this study aims to investigate this association. Methods After obtaining approval from the ethics committee, we conducted a retrospective study that involved all patients who attended our hospital, and who underwent fine-needle aspiration cytology for the evaluation of suspicious thyroid nodules (TR3-5). Electronic medical records were used to obtain data about the ultrasound and cytology reports. A multivariable binary logistic regression analysis model was conducted to identify the independent factors significantly associated with malignant thyroid nodules. Results The study included 366 patients who un

Impact of early presentation on disease outcomes in children

Frontiers | Case Report: Jejunoileal Atresia With Persistent Poor Bowel Function Can Occur After Surgical Correction for Hirschsprung Disease

Jejunoileal atresia (JIA) is one of the common etiologies of intestinal obtrusion in neonates. However, cases of concomitant ileal atresia and Hirschsprung disease rarely occur. We report the case of a male infant who had JIA concomitantly with Hirschsprung disease that was re-anastomosed. The patient underwent an exploratory laparotomy to resect the dilated terminal ileum. Subsequently, owing to a significantly dilated proximal bowel, he underwent a second exploratory laparotomy. However, he continued to have feeding intolerance postoperatively. He had colonic aganglionosis and was diagnosed with Hirschsprung disease. A third laparotomy was then performed. Additionally, he had recurrent episodes of gram-negative bacteremia, especially candida parapsilosis fungemia, despite receiving antibiotics and antifungal, and there were no identifiable underlying genetic or immunological causes. Finally, the patient had recurrent episodes of hypoglycemia, central hypothyroidism, and multiple orga

Man burns his wife and child with acid in Jeddah

The security services began investigating the incident, noting that family disputes were the reason behind the attack by the accused, a Saudi national, on his wife inside their house in Jeddah.

Saudi Arabia approves COVID-19 vaccine for kids ages 5 to 11

MAKKAH: The Saudi Food and Drug Authority on Wednesday approved the use of the Pfizer-BioNTech COVID-19 vaccine for children between the ages of 5 and 11. Many countries have already approved the use of vaccines for children ages 12 and over. In some, attention is now turning to expanding vaccination eligibility to include younger children, following research into their safety

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