The patients received the AstraZeneca jab in Ipswich, Toowoomba and Bundaberg but have since recovered.
All four had histories of severe allergic reactions or anaphylaxis.
Health officials have assured the public that such reactions among people with severe allergies are to be expected.
Four people in Queensland have suffered anaphylaxis after receiving the Covid-19 vaccine within the last 48 hours (healthcare worker prepares dose of AstraZeneca vaccine)
Dr John Wakefield, Director-General of Queensland Health, said people who have allergies that can trigger anaphylaxis may choose to delay getting the vaccine until authorities get to the bottom of this . We expect with a vaccination program, to see allergic reactions, he said.
Two people in Western Australia have suffered severe allergic reactions soon after receiving the COVID-19 vaccination, the state s Chief Health Officer has revealed in the wake of four recent similar events in Queensland.
The Therapeutic Goods Administration, which is responsible for approving vaccines in Australia, is closely reviewing anaphylaxis reports, but stresses it is a very rare side effect that may occur with any vaccine .
While all four Queensland reactions came after receiving shots from a single batch of the AstraZeneca vaccine, WA Chief Health Officer Dr Andrew Robertson said one case in his state involved that vaccine and the other followed the injection of the Pfizer jab.
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Brisbane s hospital, aged care facilities and disability providers are also set to come out lockdown on Friday after the state recorded no new cases of community virus transmission.
The lockdown began when a doctor tested positive on Friday after working at Princess Alexandra Hospital and visiting four venues in the city s south on Thursday.
The woman was infected by a patient who also infected a person staying in a separate room at Brisbane s Hotel Grand Chancellor quarantine facility.
Ms D ath said about 330 of 428 close contacts of the doctor have tested negative for the virus, while no other cases have been reported among PA hospital staff or hotel workers and guests.