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Page 4 - Jian Jin News Today : Breaking News, Live Updates & Top Stories | Vimarsana

atelier diameter adds arch motifs to art gallery extension in nanjing, china

Handheld sensor helps farmers monitor crops with precision

Celebrating prolific Purdue University inventors

Happy National Inventors Day! This day was created via Presidential Proclamation 4187 in 1973 not even 50 years ago! Read the complete proclamation online. At Purdue Research Foundation, we work…

Cullinan Oncology Forms Strategic Collaboration Agreement with Mount Sinai to Advance Oral HPK1 Protein Degrader for Cancer Treatment

Collaboration to identify and advance best-in-class HPK1 protein degraders Exclusive option for Cullinan to license related intellectual property from the collaboration CAMBRIDGE, Mass.,. | January 10, 2022

Pediatric Leukemia Drug Candidate Benefits from Structure-Based Design

Researchers at Mount Sinai, New York, have used a structure-based designing approach to develop a small-molecule chimera called MS67 that targets protein degradation mechanisms and selectively breaks down WDR5, a chromatin binding protein that contributes to tumorigenesis of a wide range of human cancers including both solid tumors and blood cancers. The study establishes the superiority of pharmacological degradation of WDR5 as a promising therapeutic strategy for treating WDR5-dependent tumors over earlier strategies that employed WDR5 inhibitors.

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