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Novel small-molecule therapy shows promise against deadly pediatric leukemia

Mount Sinai researchers have developed a therapy that shows promise against a deadly pediatric leukemia. The small-molecule therapy was highly effective in fighting a type of acute myeloid leukemia in both in vitro and in vivo experiments, according to research published in Science Translational Medicine in September.

Jian jinAneel aggarwalGreg wangEmily hendersonUniversity of north carolina at chapel hillIcahn school of medicine at mount sinaiProfessor of pharmacological sciencesMount sinai centerOncological sciencesTisch cancer institute at mount sinaiScience translational medicineMount sinai professorTherapeutics discoveryIcahn schoolNorth carolinaChapel hill

El hotel de lujo más alto del mundo abre sus puertas en China

El hotel de lujo más alto del mundo abre sus puertas en China
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Novel therapy of pharmacological degradation of AKT might be effective in many cancers- Edexlive

Representative Image | Pic: Express A team of researchers has developed a novel therapy that could be effective for different types of cancers. The study, published in the journal Cancer Discovery, indicates that the therapeutic agent shows high effectiveness in vitro at disrupting a biological pathway that helps cancer survive. Translating these findings into effective cancer therapies for patients is a high priority, said researcher Jian Jin from Mount Sinai in the US. According to the researchers, the therapy is an engineered molecule, MS21, that causes the degradation of AKT, an enzyme that is overly active in many cancers. This study laid out evidence that pharmacological degradation of AKT is a viable treatment for cancers with mutations in certain genes, the researchers said.

Jian jinRamon parsonsCancer discoveryMount sinaiஜியான் ஜின்ராமன் பார்சன்கள்புற்றுநோய் கண்டுபிடிப்புஏற்ற சினை

Novel therapy might be effective in many cancers

Novel therapy might be effective in many cancers By IANS | 0 Views High-Fibre Diet May Lower Colon Cancer Risk. Image Source: IANS News New York, July 25 : A team of researchers has developed a novel therapy that could be effective for different types of cancers. The study, published in the journal Cancer Discovery, indicates that the therapeutic agent shows high effectiveness in vitro at disrupting a biological pathway that helps cancer survive. Translating these findings into effective cancer therapies for patients is a high priority., said researcher Jian Jin from Mount Sinai in the US. According to the researchers, the therapy is an engineered molecule, MS21, that causes the degradation of AKT, an enzyme that is overly active in many cancers.

New yorkUnited statesJian jinRamon parsonsCancer discoveryMount sinaiபுதியது யார்க்ஒன்றுபட்டது மாநிலங்களில்ஜியான் ஜின்ராமன் பார்சன்கள்புற்றுநோய் கண்டுபிடிப்புஏற்ற சினை

Novel therapeutic agent could be effective for treating cancers with certain gene mutations

Novel therapeutic agent could be effective for treating cancers with certain gene mutations Mount Sinai researchers have developed a therapeutic agent that shows high effectiveness in vitro at disrupting a biological pathway that helps cancer survive, according to a paper published in Cancer Discovery, a journal of the American Association for Cancer Research, in July. The therapy is an engineered molecule, named MS21, that causes the degradation of AKT, an enzyme that is overly active in many cancers. This study laid out evidence that pharmacological degradation of AKT is a viable treatment for cancers with mutations in certain genes. Related Stories

United statesJian jinRamon parsonsEmily hendersonCancer researchAmerican association for cancer researchIcahn school of medicine at mount sinaiTisch cancer instituteMount sinai centerOncological sciencesCancer discoveryAmerican associationWard coleman chairIcahn schoolMount sinai professorTherapeutics discovery