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JScreen Is Making Cancer Genetic Testing Accessible

JScreen Is Making Cancer Genetic Testing Accessible Ashkenazi men and women face a 1-in-40 risk of carrying mutations in the BRCA1 and BRCA2 genes (genes linked to breast, ovarian, prostate, pancreatic and melanoma cancers) more than 10 times the risk in the general population. JScreen, a national public health initiative based at Emory University, Atlanta, has announced what could be a major breakthrough: a program that offers at-home testing for more than 60 cancer susceptibility genes linked to certain hereditary risks. “This type of testing is important because it alerts people to their risks before they get cancer,” explained Jane Lowe Meisel, MD, an associate professor at Emory’s School of Medicine. “They can then take action to help prevent cancer altogether or to detect it at an early, treatable stage.”

Black women with breast cancer show high comorbidity rates

December 10, 2020 Black women had high rates of health conditions linked to worse breast cancer outcomes in a study published on December 7 in Cancer. These trends could be contributing to worse breast cancer outcomes for Black women despite years of better treatment options and widespread screening mammography. The retrospective study, led by Kirsten Nyrop, PhD, looked at differences among 548 Black and white women diagnosed with early-stage breast cancer. Black patients had higher rates of hypertension, high cholesterol, and diabetes at diagnosis, even after the authors adjusted for age and body mass index (BMI) score. Both obesity and HR+ breast cancers have been rising in the U.S. for decades. While new treatments and widespread screening mammography have resulted in better breast cancer outcomes overall, Black women are still more likely to die from breast cancer than white women.

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